Synthesis, characterization, and anticancer potential of pyrene-appended Schiff base tin(<scp>iv</scp>) complexes: experimental and computational insights-Reference-Cited by-同舟云学术

Synthesis, characterization, and anticancer potential of pyrene-appended Schiff base tin(iv) complexes: experimental and computational insights

Published:2024 Issue: Volume: Page:
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Paul Anup¹^ORCID,Khan Rais Ahmad²^ORCID,Shaik Gouse M.³,Shaik Jilani P.³,Nesterov Dmytro S.¹^ORCID,Guedes da Silva M. Fátima C.¹⁴^ORCID,Pombeiro Armando J. L.¹^ORCID

Affiliation:

1. Centro de Química Estrutural, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal

2. Department of Chemistry, King Saud University, Riyadh-11451, Kingdom of Saudi Arabia

3. Department of Biochemistry, King Saud University, Riyadh-11451, Kingdom of Saudi Arabia

4. Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal

Abstract

The cytotoxicity of two novel triorganotin(iv) compounds featuring pyrene-appended Schiff base groups is demonstrated, and molecular docking analysis indicates that they exhibit interactions with MMP-2 and TGF-β proteins.

Funder

Fundação para a Ciência e a Tecnologia

Instituto Superior Técnico

King Saud University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ04401G

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