Electrocatalytic oxidative C–H cycloamination towards tricyclic [1,2,4]triazolo-[3,4-i]purine nucleosides mediated by bromide ions

Author:

Yang Qi-Liang1ORCID,Li Wan-Wan1,Zhang Zhong-Xu1,Zhang Han-Meng1,Li Xian-Jia1,Guo Hai-Ming1ORCID

Affiliation:

1. State Key Laboratory of Antiviral Drugs, Pingyuan Laboratory, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China

Abstract

A green and sustainable electrochemical alternative strategy for the synthesis of biologically important [1,2,4]-triazolo-[3,4-i]-purine derivatives via intramolecular oxidative C–N bond coupling has been established.

Funder

Henan Normal University

National College Students Innovation and Entrepreneurship Training Program

Henan Key Laboratory of Organic Functional Molecules and Drug Innovation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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