High-precision rapid testing of omicron SARS-CoV-2 variants in clinical samples using AI-nanopore-Reference-Cited by-同舟云学术

High-precision rapid testing of omicron SARS-CoV-2 variants in clinical samples using AI-nanopore

Published:2023 Issue:22 Volume:23 Page:4909-4918
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Murakami Kaoru¹²,Kubota Shimpei I.¹²,Tanaka Kumiko¹,Tanaka Hiroki¹,Akabane Keiichiroh¹,Suzuki Rigel³,Shinohara Yuta¹,Takei Hiroyasu⁴,Hashimoto Shigeru¹,Tanaka Yuki²,Hojyo Shintaro¹²,Sakamoto Osamu⁴,Naono Norihiko⁴,Takaai Takayui⁵,Sato Kazuki¹⁶,Kojima Yuichi¹⁶,Harada Toshiyuki⁷,Hattori Takeshi⁸,Fuke Satoshi⁹,Yokota Isao¹⁰,Konno Satoshi⁶,Washio Takashi⁵,Fukuhara Takasuke³,Teshima Takanori¹¹¹²^ORCID,Taniguchi Masateru⁵^ORCID,Murakami Masaaki¹²¹³^ORCID

Affiliation:

1. Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo 060-0815, Japan

2. Group of Quantum immunology, Institute for Quantum Life Science, National Institute for Quantum and Radiological Science and Technology (QST), Chiba 263-8555, Japan

3. Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, 060-0815, Japan

4. Aipore Inc., 26-1 Sakuragaokacho, Shibuya, Tokyo 150-8512, Japan

5. The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, 567-0047, Osaka, Japan

6. Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan

7. Department of Respiratory Medicine, Japan Community Healthcare Organization Hokkaido Hospital, Sapporo, 062-8618, Japan

8. Department of Respiratory Medicine, Hokkaido Medical Center, National Hospital Organization, Sapporo, 063-0005, Japan

9. Department of Respiratory Medicine, KKR Sapporo Medical Center, Sapporo, 062-0931, Japan

10. Department of Biostatistics, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan

11. Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, 060-8638, Japan

12. Department of Hematology, Faculty of Medicine, Hokkaido University, Sapporo, 060-8638, Japan

13. Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo 001-0020, Japan

Abstract

Our results demonstrate the AI-nanopore platform is an effective diagnostic tool for SARS-CoV-2 variants including the next pandemic.

Funder

Japan Agency for Medical Research and Development

Hokkaido University

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00572K

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