Reliable, standardized measurements for cell mechanical properties

Author:

Pérez-Domínguez Sandra1,Kulkarni Shruti G.1ORCID,Pabijan Joanna2,Gnanachandran Kajangi2ORCID,Holuigue Hatice3ORCID,Eroles Mar4,Lorenc Ewelina3ORCID,Berardi Massimiliano56,Antonovaite Nelda6,Marini Maria Luisa7,Lopez Alonso Javier7,Redonto-Morata Lorena7ORCID,Dupres Vincent7,Janel Sebastien7ORCID,Acharya Sovon8,Otero Jorge910,Navajas Daniel910,Bielawski Kevin6,Schillers Hermann8,Lafont Frank7ORCID,Rico Felix4ORCID,Podestà Alessandro3ORCID,Radmacher Manfred1,Lekka Małgorzata2ORCID

Affiliation:

1. Institute of Biophysics, University of Bremen, 28359, Bremen, Germany

2. Department of Biophysical Microstructures, Institute of Nuclear Physics, Polish Academy of Sciences, PL-31342 Kraków, Poland

3. Department of Physics “Aldo Pontremoli” and CIMAINA, University of Milano, via Celoria 16, 20133 Milano, Italy

4. Aix-Marseille Univ., CNRS, INSERM, LAI, Turing Centre for Living Systems, Marseille, France

5. Laserlab, Department of Physics and Astronomy, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV, Amsterdam, The Netherlands

6. Optics11 Life, Hettenheuvelweg 37-39, 1101 BM, Amsterdam, The Netherlands

7. Université de Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019-UMR9017, CIIL—Center for Infection and Immunity of Lille, F-59000 Lille, France

8. Institute of Physiology II, University Muenster, Robert-Koch-Str. 27b, 48149 Münster, Germany

9. Institute for Bioengineering of Catalonia and Universitat de Barcelona, Barcelona, Spain

10. CIBER de Enfermedades Respiratorias, Madrid, Spain

Abstract

The standardized approach in nanoindentation measurements provides a reproducible mechanical characterization of cancer cells.

Funder

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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