Benzimidazole-based ionic and non-ionic organoselenium compounds: innovative synthetic strategies, structural characterization and preliminary anti-proliferative activities

Author:

Banerjee Kaustav1ORCID,Bhattacherjee Debojit2ORCID,Raina Khyati3ORCID,Thummer Rajkumar P.3ORCID,Bhabak Krishna Pada124ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India

2. Centre for the Environment, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India

3. Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India

4. Jyoti and Bhupat Mehta School of Health Sciences and Technology, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India

Abstract

Rational design of and efficient synthesis of innovative benzimidazole-based ionic and non-ionic organoselenium compounds is described. The compounds were studied for their anti-proliferative activities against triple-negative breast cancer cells.

Funder

Science and Engineering Research Board

Indian Council of Medical Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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