Gated nanoprobe utilizing metal–organic frameworks for identifying and distinguishing between the wild strains and the vaccine strains of brucella

Author:

Li Dong1,Ren Shuna1,Wang Xiaotong1,Chen Lili1,You Shuang1,Tang Yan2,Chen Lihua1ORCID

Affiliation:

1. Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science; Shandong Key Laboratory of Biochemical Analysis; Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong; Key Laboratory of Eco-chemical Engineering; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China

2. Xinjiang Agricultural vocational Technical College; Institute of Western Agriculture, the Chinese Academy of Agricultural sciences, PR China

Abstract

A novel gated nanoprobe using MOF as a scaffold and hairpin DNA as a "gating switch". It is used to confirm the strain type of brucella.

Publisher

Royal Society of Chemistry (RSC)

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