Dispersed single wall carbon nanotubes do not impact mitochondria structure or function, but technical issues during analysis could yield incorrect results-Reference-Cited by-同舟云学术

Dispersed single wall carbon nanotubes do not impact mitochondria structure or function, but technical issues during analysis could yield incorrect results

Published:2017 Issue:2 Volume:5 Page:369-374
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Holt Brian D.¹²³⁴^ORCID,Roginskaya Vera⁵⁶⁷³⁴,Van Houten Bennett⁵⁶⁷³⁴,Islam Mohammad F.⁸²³⁴^ORCID,Dahl Kris Noel⁹²³⁴

Affiliation:

1. Department of Biomedical Engineering

2. Carnegie Mellon University

3. Pittsburgh

4. USA

5. Department of Pharmacology and Chemical Biology

6. University of Pittsburgh School of Medicine and The University of Pittsburgh Cancer Institute

7. Hillman Cancer Center

8. Department of Materials Science and Engineering

9. Department of Chemical Engineering

Abstract

Mitochondria, which generate cellular energy, are not influenced by purified carbon nanotubes. Many traditional biological assays to determine mitochondria function give false results because of nanotube surface activity and optical interference.

Funder

Division of Civil, Mechanical and Manufacturing Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C6TB02180H

Reference29 articles.

1. Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery

2. Subcellular Partitioning and Analysis of Gd3+-Loaded Ultrashort Single-Walled Carbon Nanotubes

3. Quantification of Uptake and Localization of Bovine Serum Albumin-Stabilized Single-Wall Carbon Nanotubes in Different Human Cell Types

4. Carbon nanotubes for delivery of small molecule drugs

5. Differential sub-cellular processing of single-wall carbon nanotubes via interfacial modifications

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