Recognition of hydrophilic molecules in deep cavitand hosts with water-mediated hydrogen bonds

Author:

Guan Hua-Wei1,Zhu Yu-Jie1,Peters Joannes2,Brea Oriana2,Himo Fahmi2,Rebek Julius3,Yu Yang1ORCID

Affiliation:

1. Center for Supramolecular Chemistry & Catalysis and Department of Chemistry, College of Science, Shanghai University, 99 Shang-Da Road, Shanghai 200444, China

2. Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691, Stockholm, Sweden

3. Department Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 210550 North Torrey Pines Road, La Jolla, CA 92037, USA

Abstract

A new supramolecular system was constructed based on water-mediated hydrogen bonding between a benzimidazole functionalized host, water and guest. Intriguingly, these hosts can recognize small hydrophilic guests in water through the synergistic action of water-mediated hydrogen bonding and hydrophobic effects.

Funder

National Natural Science Foundation of China

Shanghai University

Vetenskapsrådet

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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