Gadolinium complexes of macrocyclic diethylenetriamine-N-oxide pentaacetic acid-bisamide as highly stable MRI contrast agents with high relaxivity-Reference-Cited by-同舟云学术

Gadolinium complexes of macrocyclic diethylenetriamine-N-oxide pentaacetic acid-bisamide as highly stable MRI contrast agents with high relaxivity

Published:2020 Issue:26 Volume:49 Page:8927-8932
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Xu Kehan¹²³⁴⁵,Xu Na¹²³⁴⁵,Zhang Beibei¹²³⁴⁵,Tang Weijun⁶⁷⁴⁵,Ding Yun¹²³⁴⁵,Hu Aiguo¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Key Laboratory of Advanced Polymeric Materials

2. School of Materials Science and Engineering

3. East China University of Science and Technology

4. Shanghai

5. China

6. Department of Radiology

7. Huashan Hospital Affiliated to Fudan University

Abstract

Macrocyclic gadolinium(iii) complexes with hyphenated-amino-N-oxide (HAO) type ligand structures are designed as efficient magnetic resonance imaging (MRI) contrast agents (CAs) with high relaxivity and stability.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Shanghai Leading Academic Discipline Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/DT/D0DT00248H

Reference42 articles.

1. Strategies for increasing the sensitivity of gadolinium based MRI contrast agents

2. Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications

3. High-Relaxivity MRI Contrast Agents: Where Coordination Chemistry Meets Medical Imaging

4. Alternatives to Gadolinium-Based Metal Chelates for Magnetic Resonance Imaging

5. The Transition from Metal-Based to Metal-Free Contrast Agents for T1 Magnetic Resonance Imaging Enhancement

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