DBU-catalyzed substitution-controlled synthesis of oxa[3.3.1] bridged ring and naphthylamine derivatives-Reference-Cited by-同舟云学术

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DBU-catalyzed substitution-controlled synthesis of oxa[3.3.1] bridged ring and naphthylamine derivatives

Published:2024 Issue:10 Volume:11 Page:2845-2850
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xu Shiyu¹,Sun Zhihui¹,Liu Pengyutian²,Wei Yuanlin¹,Sun Fan¹,Zhao Man²,Wang Ying²,Zhang Ming²,Li Guofeng²^ORCID,Liang Hong¹^ORCID

Affiliation:

1. Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, China

2. School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518055, China

Abstract

A switchable cascade cyclization reaction of ortho-alkynyl arylketones with amines has been developed, where the different reaction pathways are controlled by the substituent on the α-carbon of in-situ-generated ortho-alkynyl arylaldimines.

Funder

National Natural Science Foundation of China

Lanzhou University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00012A

Reference42 articles.

1. Molecular complexity and fragment-based drug discovery: ten years on

2. A Copper-Catalyzed Decarboxylative Amination/Hydroamination Sequence: Switchable Synthesis of Functionalized Indoles

3. Redox-Divergent Hydrogen-Retentive or Hydrogen-Releasing Synthesis of 3,4-Dihydroisoquinolines or Isoquinolines

4. Photoredox Activation of Anhydrides for the Solvent‐Controlled Switchable Synthesis of gem ‐Difluoro Compounds**

5. Switchable Divergent Synthesis Using Photocatalysis

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