Biomimetic nanoscale metal–organic framework harnesses hypoxia for effective cancer radiotherapy and immunotherapy-Reference-Cited by-同舟云学术

Biomimetic nanoscale metal–organic framework harnesses hypoxia for effective cancer radiotherapy and immunotherapy

Published:2020 Issue:29 Volume:11 Page:7641-7653
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ni Kaiyuan¹²³⁴,Lan Guangxu¹²³⁴,Song Yang¹²³⁴,Hao Ziyang¹²³⁴,Lin Wenbin¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. The University of Chicago

3. Chicago

4. USA

5. Department of Radiation and Cellular Oncology

Abstract

Biomimetic Hf-DBP-Fe harnesses tumor hypoxia for cancer treatment via RT-RDT and CDT as well as synergistic combination with immune checkpoint blockade.

Funder

National Cancer Institute

U.S. Department of Defense

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01949F

Reference55 articles.

1. Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

2. Targeting hypoxia in cancer therapy

3. Hypoxia, DNA repair and genetic instability

4. Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

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