Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters

Author:

Vong Kenward K. H.1234,Tsubokura Kazuki12345,Nakao Yoichi56784,Tanei Tomonori91011124,Noguchi Shinzaburo91011124,Kitazume Shinobu13141523,Taniguchi Naoyuki13141523,Tanaka Katsunori123416ORCID

Affiliation:

1. Biofunctional Synthetic Chemistry Laboratory

2. RIKEN

3. Saitama

4. Japan

5. School of Advanced Science and Engineering

6. Department of Chemistry and Biochemistry

7. Waseda University

8. Tokyo

9. Department of Breast and Endocrine Surgery

10. Graduate School of Medicine

11. Osaka University

12. Osaka

13. Disease Glycomics Team

14. Global Research Cluster

15. RIKEN-Max Planck Joint Research Center for Systems Chemical Biology

16. Biofunctional Chemistry Laboratory

Abstract

Glycine propargyl ester reactivity shows evidence for selective polyamine reactivity, leading to a new strategy for cancer cell targeting.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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