Successive addition of two different Grignard reagents to nitriles: access to α,α-disubstituted propargylamine derivatives-Reference-Cited by-同舟云学术

Successive addition of two different Grignard reagents to nitriles: access to α,α-disubstituted propargylamine derivatives

Published:2018 Issue:9 Volume:16 Page:1519-1526
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Caillé Julien¹²³⁴⁵,Boukattaya Fatma¹²³⁴⁵,Boeda Fabien¹²³⁴⁵^ORCID,Pearson-Long Morwenna S. M.¹²³⁴⁵^ORCID,Ammar Houcine⁶⁷⁸⁹¹⁰,Bertus Philippe¹²³⁴⁵^ORCID

Affiliation:

1. Le Mans Université (Université du Maine)

2. CNRS UMR 6283

3. Institut des Molécules et Matériaux du Mans (IMMM)

4. 72085 Le Mans Cedex 09

5. France

6. Laboratoire de Chimie Appliquée: Hétérocycles

7. Corps Gras et Polymères

8. Faculty of Science of Sfax

9. University of Sfax

10. Sfax

Abstract

The successive addition of two different Grignard reagents to acyl cyanohydrins was performed with success by using alkynyl Grignard reagents.

Funder

Ministère de l'Enseignement Supérieur et de la Recherche Scientifique

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB03047A

Reference40 articles.

1. Recent approaches to the construction of 1-azaspiro[4.5]decanes and related 1-azaspirocycles

2. Quaternary centres bearing nitrogen (α-tertiary amines) as products of molecular rearrangements

3. Catalytic Asymmetric Electrophilic Amination Reactions To Form Nitrogen-Bearing Tetrasubstituted Carbon Stereocenters

4. Synthetic approaches towards alkaloids bearing α-tertiary amines

5. Double Addition of Organometallics to Nitriles: Toward an Access to Tertiary Carbinamines

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