Complex coacervation-based loading and tunable release of a cationic protein from monodisperse glycosaminoglycan microgels

Author:

Schuurmans Carl C. L.12345,Abbadessa Anna12345,Bengtson Mikkel A.12345,Pletikapic Galja6789,Eral Huseyin Burak101112913,Koenderink Gijsje6789ORCID,Masereeuw Rosalinde142345,Hennink Wim E.12345ORCID,Vermonden Tina12345ORCID

Affiliation:

1. Department of Pharmaceutics

2. Utrecht Institute for Pharmaceutical Sciences (UIPS)

3. Science for Life

4. Utrecht University

5. 3508 TB Utrecht

6. Biological Soft Matter Group

7. AMOLF

8. Amsterdam

9. The Netherlands

10. Process and Energy Department

11. Delft University of Technology

12. Delft

13. Van’t Hoff Laboratory for Physical and Colloid Chemistry

14. Department of Pharmacology

Abstract

Glycosaminoglycan-based microgels are of interest for biomedical applications because of their ability to retain and gradually release bioactive cationic proteins.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Seventh Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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