Structure–activity relationship of avocadyne-Reference-Cited by-同舟云学术

Structure–activity relationship of avocadyne

Published:2021 Issue: Volume: Page:
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Tcheng Matthew¹²³⁴,Cunha Vitor L. S.⁵⁶⁷⁸⁴,Ahmed Nawaz¹²³⁴,Liu Xiaofan⁹¹⁰¹¹¹²,Smith Richard W.¹³⁵¹⁴⁴,Rea Kevin A.¹⁵⁹¹⁰¹¹¹²,Akhtar Tariq A.¹⁵⁹¹⁰¹¹¹²,D'Alessandro Angelo¹⁶¹⁷¹⁸¹²,Minden Mark D.¹⁹²⁰²¹⁴,Vockley Jerry²²²³²⁴²⁵²⁶,O'Doherty George A.⁹¹⁰¹¹¹²,Lowary Todd L.⁵⁶⁷⁸⁴^ORCID,Spagnuolo Paul A.¹²³⁴^ORCID

Affiliation:

1. Department of Food Science

2. University of Guelph

3. Guelph

4. Canada

5. Department of Chemistry

6. University of Alberta

7. 4-008 Centennial Centre for Interdisciplinary Science

8. Edmonton

9. Department of Biochemistry and Chemical Biology

10. Northeastern University

11. Boston

12. USA

13. University of Waterloo Mass Spectrometry Facility

14. Waterloo

15. Department of Molecular and Cellular Biology

16. Department of Biochemistry and Molecular Genetics

17. University of Colorado Anschutz Medical Campus

18. Aurora

19. Princess Margaret Cancer Center

20. Ontario Cancer Institute

21. Toronto

22. Department of Pediatrics and Center for Rare Disease Therapy

23. UPMC

24. Children's Hospital of Pittsburgh

25. University of Pittsburgh

26. Pittsburgh

Abstract

Structural components including the terminal triple bond, the presence and (R)-stereochemistry of the hydroxyl groups, and number of carbons in avocadyne's aliphatic linear chain are critical to its ability to modulate fatty acid oxidation.

Funder

Cancer Research Society

Natural Sciences and Engineering Research Council of Canada

Ontario Institute for Cancer Research

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO00693B

Reference36 articles.