Antiproliferative activity of novel isatinyl/indanyl nitrones (INs) as potential spin trapping agents of free radical intermediates-Reference-Cited by-同舟云学术

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Antiproliferative activity of novel isatinyl/indanyl nitrones (INs) as potential spin trapping agents of free radical intermediates

Published:2018 Issue:2 Volume:9 Page:299-304
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Maiuolo Loredana¹²³⁴^ORCID,Feriotto Giordana⁵⁶⁷⁴^ORCID,Algieri Vincenzo¹²³⁴^ORCID,Nardi Monica¹²³⁴⁸^ORCID,Russo Beatrice¹²³⁴^ORCID,Di Gioia Maria Luisa⁹¹⁰²³⁴^ORCID,Furia Emilia¹²³⁴^ORCID,Tallarida Matteo Antonio¹²³⁴^ORCID,Mischiati Carlo¹¹⁶⁷⁴^ORCID,De Nino Antonio¹²³⁴^ORCID

Affiliation:

1. Dipartimento di Chimica e Tecnologie Chimiche

2. Università della Calabria

3. 87036 Rende (CS)

4. Italy

5. Dipartimento di Scienze Chimiche e Farmaceutiche

6. Università di Ferrara

7. 44121 Ferrara

8. Dipartimento di Agraria

9. Dipartimento di Farmacia e Scienze della Salute e della Nutrizione

10. Edificio Polifunzionale

11. Dipartimento di Scienze Biomediche e Chirurgico Specialistiche

Abstract

Isatinyl and indanyl nitrones (INs) were synthesized and evaluated for their antiproliferative activity and antioxidant properties.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

University of Calabria

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C7MD00537G

Reference36 articles.

1. Exploring biology with small organic molecules

2. 2-Hydroxybenzamide as a Ligand. Complex Formation with Dioxouranium(VI), Aluminum(III), Neodymium(III), and Nickel(II) Ions

3. Speciation of 2-Hydroxybenzoic Acid with Calcium(II), Magnesium(II), and Nickel(II) Cations in Self-Medium

4. Anti-Cancer Activity of Nitrones and Observations on Mechanism of Action

5. Application of Spin Traps to Biological Systems

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