A double rare earth doped CD nanoplatform for nanocatalytic/starving-like synergistic therapy with GSH-depletion and enhanced reactive oxygen species generation

Abstract

Ce–Gd@CDs–GOx can promote generation of ˙OH and oxidation of glucose, achieving nanocatalytic anticancer activities and starving-like synergistic therapy. Ce ions can decompose H2O2 to relieve hypoxia and deplete GSH, for precise treatment using T1-weighted MR imaging.