Glutathione displacement assay based on a fluorescent Au(<scp>i</scp>) complex-Reference-Cited by-同舟云学术

Glutathione displacement assay based on a fluorescent Au(i) complex

Published:2023 Issue:31 Volume:11 Page:7344-7352
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Lee Shinae¹²,Heo Seunga²,Park Jihwan³⁴,Heo Jeongyun³,Kim Sehoon³⁴^ORCID,You Youngmin¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 03722, Republic of Korea

2. Division of Chemical Engineering and Materials Science, Ewha Womans University, Seoul 03760, Republic of Korea

3. Chemical and Biological Integrative Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea

4. KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea

Abstract

A two-coordinate homoleptic gold(i) complex having carbene ligands shows a fluorescence turn-on response to glutathione, enabling fluorescence discrimination of senescent cells over healthy preadipocytes.

Funder

Korea Institute of Science and Technology Information

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB00953J

Reference49 articles.

1. Oxidized Redox State of Glutathione in the Endoplasmic Reticulum

2. Recent progress in luminescent and colorimetric chemosensors for detection of thiols

3. BODIPY-Based Ratiometric Fluorescent Sensor for Highly Selective Detection of Glutathione over Cysteine and Homocysteine

4. Dithiol Proteins as Guardians of the Intracellular Redox Milieu in Parasites: Old and New Drug Targets in Trypanosomes and Malaria-Causing Plasmodia

5. REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN

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