Hybrid bio-nanoporous peptide loaded-polymer platforms with anticancer and antibacterial activities

Author:

Icriverzi Madalina1ORCID,Florian Paula Ecaterina1ORCID,Bonciu Anca2ORCID,Dumitrescu Luminita Nicoleta2,Moldovan Antoniu2,Pelinescu Diana3,Ionescu Robertina3,Avram Ionela3ORCID,Munteanu Cristian V. A.1ORCID,Sima Livia Elena1,Dinca Valentina2ORCID,Rusen Laurentiu2ORCID,Roseanu Anca1ORCID

Affiliation:

1. Institute of Biochemistry of the Romanian Academy, 060031 Bucharest, Romania

2. National Institute for Lasers, Plasma, and Radiation Physics, 409 Atomistilor Street, 077125 Magurele, Romania

3. Faculty of Biology, University of Bucharest, Department of Genetics, Intrarea Portocalelor no. 1-3, Sector 6, Bucharest, Romania

Abstract

pNIPAM-co-BA coatings featuring nanopore biointerfaces obtained vis laser methods incorporating magainin/melittin peptides impair bacterial growth and reduce cancer cell proliferation.

Funder

Ministry of Education and Research, Romania

Publisher

Royal Society of Chemistry (RSC)

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