Constructing a passive targeting and long retention therapeutic nanoplatform based on water-soluble, non-toxic and highly-stable core–shell poly(amino acid) nanocomplexes-Reference-Cited by-同舟云学术

Constructing a passive targeting and long retention therapeutic nanoplatform based on water-soluble, non-toxic and highly-stable core–shell poly(amino acid) nanocomplexes

Published:2021 Issue:21 Volume:9 Page:7065-7075
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Wang Xin¹,Deng Bingqing²,Yu Meng²,Zeng Tao¹,Chen Yuyu²,Hu Jianqiang²^ORCID,Wu Qianqing²,Li Aiqing¹^ORCID

Affiliation:

1. State Key Laboratory of Organ Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Key Laboratory of Renal Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China

2. Nanobiological Medicine Center, Key Lab of Fuel Cell Technology of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, China

Abstract

A water-soluble, non-toxic, stable, passive kidney targeting, slow-released and long retentive therapeutic nanoplatform of core–shell gefitinib/poly(ethylene glycol)-polytyrosine nanocomplexes (Gef-PY NCs) is designed and constructed.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangzhou Science, Technology and Innovation Commission

Science and Technology Planning Project of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM01246K

Reference53 articles.