Tetrad-binding ligands do not bind specifically to left-handed G-quadruplexes-Reference-Cited by-同舟云学术

Tetrad-binding ligands do not bind specifically to left-handed G-quadruplexes

Published:2022 Issue:80 Volume:58 Page:11264-11267
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Das Poulomi¹^ORCID,Phan Anh Tuân¹²^ORCID

Affiliation:

1. School of Physical and Mathematical Sciences, Nanyang Technological University, 637371, Singapore

2. NTU Institute of Structural Biology, Nanyang Technological University, 636921, Singapore

Abstract

The characteristic T-capping feature of left-handed G-quadruplexes prevents specific binding of G4 ligands on the tetrads.

Funder

Ministry of Education - Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC03374G

Reference51 articles.

1. HELIX FORMATION BY GUANYLIC ACID

2. Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

3. G-Quartets 40 Years Later: From 5′-GMP to Molecular Biology and Supramolecular Chemistry

4. Quadruplex DNA: sequence, topology and structure

5. Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Why Are Left-Handed G-Quadruplexes Scarce?;The Journal of Physical Chemistry Letters;2024-03-13