On the intrinsic reactivity of highly potent trypanocidal cruzain inhibitors-Reference-Cited by-同舟云学术

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On the intrinsic reactivity of highly potent trypanocidal cruzain inhibitors

Published:2020 Issue:11 Volume:11 Page:1275-1284
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Bonatto Vinicius¹²³⁴⁵,Batista Pedro Henrique Jatai¹²³⁴⁵,Cianni Lorenzo¹²³⁴⁵,De Vita Daniela¹²³⁴⁵,Silva Daniel G.¹²³⁴⁵,Cedron Rodrigo¹²³⁴⁵,Tezuka Daiane Y.¹²³⁴⁵,de Albuquerque Sérgio⁶³⁷⁵,Moraes Carolina Borsoi⁸⁹¹⁰⁵,Franco Caio Haddad⁸⁹¹⁰⁵^ORCID,Lameira Jerônimo¹²³⁴⁵^ORCID,Leitão Andrei¹²³⁴⁵^ORCID,Montanari Carlos A.¹²³⁴⁵^ORCID

Affiliation:

1. Medicinal Chemistry Group

2. Institute of Chemistry of São Carlos

3. University of São Paulo

4. São Carlos/SP

5. Brazil

6. Ribeirão Preto School of Pharmaceutical Sciences

7. Ribeirão Preto

8. Laboratório Nacional de Biociências (LNBio)

9. Centro Nacional de Pesquisa em Energia e Materiais (CNPEM)

10. Campinas

Abstract

Aldehyde peptide like compounds display a bivalent reactive profile and improved antichagasic potency.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/MD/D0MD00097C

Reference52 articles.

1. Chagas disease: a new worldwide challenge

2. Trypanosoma cruzi and Chagas' Disease in the United States

3. Chagas Disease Drug Discovery

4. Chagas disease in Australia and New Zealand: risks and needs for public health interventions

5. Challenges and perspectives of Chagas disease: a review

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