One-pot conversion of cephalosporin C by using an optimized two-enzyme process
Author:
Affiliation:
1. Dipartimento di Biotecnologie e Scienze della Vita
2. Università degli Studi dell'Insubria
3. 21100 Varese
4. Italy
5. The Protein Factory
Abstract
Setup of a low cost one-pot enzymatic system to directly convert cephalosporin C into 7-aminocephalosporanic acid with high purity.
Publisher
Royal Society of Chemistry (RSC)
Subject
Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2015/CY/C4CY01522C
Reference28 articles.
1. Industrial production of β-lactam antibiotics
2. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
3. Enzymic and chemical transformations of the side chain of cephalosporin C
4. Enzymatic transformation of cephalosporin C to 7-amino-cephalosporanic acid. Part II: Single-step procedure using a coimmobilized enzyme system
5. Two-step immobilized enzyme conversion of cephalosporin C to 7-aminocephalosporanic acid
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