Fluorescent indicator displacement assay for the discovery of UGGAA repeat-targeted small molecules-Reference-Cited by-同舟云学术

Fluorescent indicator displacement assay for the discovery of UGGAA repeat-targeted small molecules

Published:2023 Issue:34 Volume:59 Page:5071-5074
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Shibata Tomonori¹^ORCID,Matsumoto Yasumasa²,Iihara Akiko²,Yamada Kazunori²,Ochiai Hiroshi²,Saito Ryo²,Kusaka Shinichi²,Kume Toshiyuki²

Affiliation:

1. Department of Regulatory Bioorganic Chemistry, SANKEN (The Institute of Scientific and Industrial Research), Osaka University, Ibaraki, Osaka 567-0047, Japan

2. Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1-1-1, Marunouchi, Chiyoda-ku, Tokyo 100-8205, Japan

Abstract

Fluorescent indicator displacement assay using selective fluorescent indicator NBD-NCD for UGGAA repeat enables the detection of the interaction between small molecules and UGGAA repeats.

Funder

Japan Society for the Promotion of Science

Mitsubishi Tanabe Pharma Corporation

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC00837A

Reference42 articles.

1. RNA and Disease

2. Noncoding RNA s in disease

3. RNA-Mediated Disease Mechanisms in Neurodegenerative Disorders

4. The chemical evolution of oligonucleotide therapies of clinical utility

5. The current landscape of nucleic acid therapeutics

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