Platinum(ii) complexes showing high cytotoxicity toward A2780 ovarian carcinoma cells

Author:

Choroba Katarzyna1234ORCID,Machura Barbara1234ORCID,Raposo Luis R.56789ORCID,Małecki Jan G.1234ORCID,Kula Slawomir1234ORCID,Pająk Michał1234,Erfurt Karol1011124,Maroń Anna M.1234ORCID,Fernandes Alexandra R.56789ORCID

Affiliation:

1. Institute of Chemistry

2. University of Silesia

3. 40-006 Katowice

4. Poland

5. UCIBIO

6. Departamento de Ciências da Vida

7. Faculdade de Ciências e Tecnologia

8. Universidade NOVA de Lisboa

9. 2829-516 Caparica

10. Department of Chemical Organic Technology and Petrochemistry

11. Silesian University of Technology

12. 44-100 Gliwice

Abstract

2,6-Bis(thiazol-2-yl)pyridines functionalized with 9-anthryl (L1), 9-phenanthryl (L2), and 1-pyrenyl (L3) groups were used for the preparation of [Pt(Ln)Cl]CF3SO3 (1–3) with high cytotoxic activity against ovarian cancer cells.

Funder

Narodowe Centrum Nauki

Ministério da Ciência, Tecnologia e Ensino Superior

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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