Monoclonal antibody capture from cell culture supernatants using epitope imprinted macroporous membranes
Author:
Affiliation:
1. Lehrstuhl für Technische Chemie II
2. Universität Duisburg-Essen
3. Essen
4. Germany
5. Faculty of Chemistry
6. Technical University of Dortmund
7. Bibitec GmbH
8. Bielefeld
9. Department of Biomedical Sciences
10. Faculty of Health and Society
Abstract
A straightforward epitope imprinting procedure is used to prepare IgG affinity membranes directly applicable to mAb capture under near process realistic conditions.
Funder
Bundesministerium für Bildung und Forschung
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA06632A
Reference33 articles.
1. Advances in the production and downstream processing of antibodies
2. Trends in Upstream and Downstream Process Development for Antibody Manufacturing
3. S. Ahuja , Handbook of bioseparations, Academic Press, Orlando, FA, 2000, vol. 2
4. An artificial protein L for the purification of immunoglobulins and Fab fragments by affinity chromatography
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