Multiple targeting strategies achieve novel protein drug delivery into proapoptosis lung cancer cells by precisely inhibiting survivin-Reference-Cited by-同舟云学术

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Multiple targeting strategies achieve novel protein drug delivery into proapoptosis lung cancer cells by precisely inhibiting survivin

Published:2020 Issue:19 Volume:12 Page:10623-10638
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Hu Fabiao¹²³⁴^ORCID,Yan Ting¹²³⁴,Guo Wei¹²³⁴,Liu Qiuli⁵⁶²³⁴,Han Myong Hun¹²³⁴⁷^ORCID,Liu Chang¹²³⁴,Liu Yuping⁵⁶²³⁴,Zheng Wenyun⁵⁶²³⁴,You Fang⁸⁹¹⁰¹¹¹²,Yang Yi¹²¹³¹¹,Zhang Wenliang¹⁴¹⁵¹⁶¹⁷,Ma Xingyuan¹²³⁴^ORCID

Affiliation:

1. State Key Laboratory of Bioreactor Engineering

2. East China University of Science and Technology

3. Shanghai 200237

4. P. R. China

5. Shanghai Key Laboratory of New Drug Design

6. School of Pharmacy

7. Department of Genetics

8. Department of Chemical and Biomolecular Engineering

9. National University of Singapore

10. Singapore 117585

11. Singapore

12. SinGENE Biotech Pte Ltd

13. Singapore 118258

14. Center of Translational Biomedical Research

15. University of North Carolina at Greensboro

16. Greensboro

17. USA

Abstract

Therapeutic recombinant proteins have numerous advantages and benefits over chemical drugs, particularly high specificity and good biocompatibility.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR01352H

Reference49 articles.

1. 2012 FDA drug approvals

2. Peptide/protein vaccine delivery system based on PLGA particles

3. Pharmacokinetics of Biotech Drugs: Peptides, Proteins and Monoclonal Antibodies

4. Recent trends in protein and peptide drug delivery systems

5. Protein drug stability: a formulation challenge

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