One-pot three-component reaction of p-quinone monoacetals, l-proline and naphthols to afford N-aryl-2-arylpyrrolidines
Author:
Affiliation:
1. State Key Laboratory of Materials-Oriented Chemical Engineering
2. College of Chemistry and Chemical Engineering
3. Nanjing Tech University
4. Nanjing 210009
5. China
Abstract
A one-pot three-component reaction of p-quinone monoacetals (or p-quinol ethers), l-proline and naphthols is developed for the synthesis of N-aryl-2-arylpyrrolidines under mild conditions with high chemo- and regioselectivity.
Funder
Natural Science Foundation of Jiangsu Province
National Natural Science Foundation of China
Nanjing Tech University
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/QO/D0QO01294G
Reference56 articles.
1. E. R. Price and S. C.Johnson , Quinones: Occurrence, medicinal uses and physiological importance , NOVA Science , New York , 2013
2. Controlled-Coupling of Quinone Monoacetals by New Activation Methods: Regioselective Synthesis of Phenol-Derived Compounds
3. Cyclohexadienone Ketals and Quinols: Four Building Blocks Potentially Useful for Enantioselective Synthesis
4. R. M. Moriarty and O.Prakash , Oxidation of Phenolic Compounds with Organohypervalent Iodine Reagents , Wiley-VCH , Weinheim, Germany , 2001 , pp 327–415
5. A Direct Route to Fluostatin C by a Fascinating Diels−Alder Reaction
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Bridged‐Ring Skeletons from Organoaluminium‐Mediated Nucleophilic Addition‐Cyclization Sequence of p‐Quinone Monoacetals and Grignard Reagents;Advanced Synthesis & Catalysis;2023-08-24
2. A One‐Pot Approach for Bio‐Based Arylamines via a Combined Photooxidative Dearomatization‐Rearomatization Strategy;Chemistry – A European Journal;2022-05-11
3. Sc(OTf) 3 ‐Catalyzed Dearomative [3+2] Annulation of 5‐Aminoisoxazoles with Quinone Imine Ketals or Quinone Monoacetals;European Journal of Organic Chemistry;2022-05-09
4. p-Quinol Ethers and p-Quinone Monoacetals as Arylation and Oxidation Reagents: Tandem N-Arylation and α-Functionalization of Pyrrolidine via Redox-Neutral Three-Component Reaction;Synthesis;2022-01-18
5. Pyrrolidine‐Catalyzed Annulations of Quinone Monoacetals with Naphthols: Synthesis of 2‐Oxabicyclo[3.3.1]nonane Skeletons, Transformations and Reaction Mechanism;Advanced Synthesis & Catalysis;2021-11-16
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3