Simultaneous quantification of marine neutral neoagaro-oligosaccharides and agar-oligosaccharides by the UHPLC-MS/MS method: application to the intestinal transport study by using the Caco-2 cell monolayer-Reference-Cited by-同舟云学术

Simultaneous quantification of marine neutral neoagaro-oligosaccharides and agar-oligosaccharides by the UHPLC-MS/MS method: application to the intestinal transport study by using the Caco-2 cell monolayer

Published:2022 Issue:22 Volume:14 Page:2227-2234
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Liu Guilin¹^ORCID,Duan Yunhai¹,Yang Shuang¹²³⁴^ORCID,Yu Mingming¹²³⁴,Lv Zhihua¹²³⁴^ORCID

Affiliation:

1. School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China

2. Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao 266003, People's Republic of China

3. Key Laboratory of Glycoscience & Glycotechnology of Shandong Province, Qingdao 266003, People's Republic of China

4. Key Laboratory of Marine Drugs, Ministry of Education of China, Qingdao 266003, People's Republic of China

Abstract

A sensitive and robust UHPLC-MS/MS method was established for the first time to simultaneously quantify marine neutral neoagaro-oligosaccharides (NAOS) and agar-oligosaccharides (AOS) with different degrees of polymerization (DP) in Hanks' balanced salt solution (HBSS).

Funder

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AY/D2AY00700B

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