Electrochemical evaluation of a boron-doped diamond electrode for simultaneous determination of an antihypertensive ternary mixture of amlodipine, hydrochlorothiazide and valsartan in pharmaceuticals

Author:

Mansano Guilherme Roberto12345,Pires Eisele Ana Paula12345,Sartori Elen Romão12345

Affiliation:

1. Universidade Estadual de Londrina (UEL)

2. Centro de Ciências Exatas

3. Departamento de Química

4. Londrina

5. Brazil

Abstract

The simultaneous voltammetric determination of amlodipine, hydrochlorothiazide and valsartan using a boron-doped diamond electrode is reported for the first time.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference42 articles.

1. J. G. Hardman , L. E.Limbird and A. G.Gilman, Goodman & Gilman's – The Pharmacological Basis of Therapeutics, McGraw-Hill, New York, 9th edn, 1996

2. Crystal Phend, Staff Writer, FDA Approves Triple-Drug Antihypertensive Polypill, Med Page Today, Washington, http://www.medpagetoday.com/ProductAlert/Prescriptions/14032

3. Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER), Exforge HCT (amlodipine/valsartan/hydrochlorothiazide) Tablets, http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm262227.htm

4. H. C. T. Exforge, Rx List, http://www.rxlist.com/exforge-hct-drug.htm

5. Development and Validation of HPLC Method for Simultaneous Determination of Amlodipine, Valsartan, Hydrochlorothiazide in Dosage Form and Spiked Human Plasma

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