Analysis of therapeutic monoclonal antibodies by imaged capillary isoelectric focusing (icIEF)-Reference-Cited by-同舟云学术

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Analysis of therapeutic monoclonal antibodies by imaged capillary isoelectric focusing (icIEF)

Published:2024 Issue:31 Volume:16 Page:5450-5458
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Sutton Haley¹,Hong Feng¹,Han Xuemei¹,Rauniyar Navin¹^ORCID

Affiliation:

1. Tanvex Biopharma USA, Inc., 10394 Pacific Center Ct, San Diego, CA 92121, USA

Abstract

Imaged capillary isoelectric focusing (icIEF) is a preferred analytical method for determining isoelectric points (pIs) and charge heterogeneity profiles in biotherapeutic proteins.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AY/D4AY00836G

Reference29 articles.

1. Charge heterogeneity of therapeutic monoclonal antibodies by different cIEF systems: views on the current situation

2. In vitro and in vivo modifications of recombinant and human IgG antibodies

3. Adaptation of the equipment for high-performance electrophoresis to isoelectric focusing

4. Theoretical and experimental study of high-performance electrophoretic mobilization of isoelectrically focused protein zones

5. Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies

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