Total syntheses of all tri-oxygenated 16-phytoprostane classes via a common precursor constructed by oxidative cyclization and alkyl–alkyl coupling reactions as the key steps-Reference-Cited by-同舟云学术

Total syntheses of all tri-oxygenated 16-phytoprostane classes via a common precursor constructed by oxidative cyclization and alkyl–alkyl coupling reactions as the key steps

Published:2017 Issue:44 Volume:15 Page:9408-9414
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Smrček Jakub¹²³⁴,Pohl Radek¹²³⁴,Jahn Ullrich¹²³⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry and Biochemistry

2. Czech Academy of Sciences

3. 16610 Prague 6

4. Czech Republic

Abstract

A parallel total synthesis of 16-F_1t-, 16-E₁-phytoprostanes and a first synthesis of 16-D_1t-phytoprostanes based on a common precursor are described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02505J

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