The strategic use of para-quinone methides to access synthetically challenging and chemoselective α,α′-diarylmethyl N-glycosides from unprotected carbohydrate amines-Reference-Cited by-同舟云学术

The strategic use of para-quinone methides to access synthetically challenging and chemoselective α,α′-diarylmethyl N-glycosides from unprotected carbohydrate amines

Published:2020 Issue:7 Volume:18 Page:1343-1348
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Sangwan Rekha¹²³⁴⁵,Dubey Atul¹²³⁴,Tiwari Ashwani¹²³⁴,Mandal Pintu Kumar¹²³⁴⁵^ORCID

Affiliation:

1. Medicinal & Process Chemistry Division

2. CSIR-Central Drug Research Institute

3. Lucknow 226031

4. India

5. Academy of Scientific and Innovative Research

Abstract

A practical route to access synthetically challenging and chemoselective α,α′-diarylmethyl N-glycosides via Sc(OTf)₃-catalyzed 1,6-conjugate addition of unprotected amino sugars with p-QMs.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00039F

Reference70 articles.

1. Site-Selective Functionalization of Hydroxyl Groups in Carbohydrate Derivatives

2. Efficient O-Functionalization of Carbohydrates with Electrophilic Reagents