Development of an amine transaminase-lipase cascade for chiral amide synthesis under flow conditions-Reference-Cited by-同舟云学术

Development of an amine transaminase-lipase cascade for chiral amide synthesis under flow conditions

Published:2023 Issue:15 Volume:25 Page:6041-6050
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Pintor Antía¹²,Mattey Ashley P.²,Lavandera Iván¹^ORCID,Gotor-Fernández Vicente¹^ORCID,Volkov Alexey²^ORCID

Affiliation:

1. Organic and Inorganic Chemistry Department. University of Oviedo. Avenida Julián Clavería 8, 33006 Oviedo, Spain

2. Enginzyme AB. Tomtebodevägen 6, 17165 Stockholm, Sweden

Abstract

An amine transaminase and a lipase have been immobilised in separated reactors containing EziG polymer-coated controlled porosity glass carrier materials to transform 1-phenoxypropan-2-one into the corresponding (R)-acetamide in organic solvent.

Funder

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/GC/D3GC02426A

Reference48 articles.

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2. Biocatalysis: Enzymatic Synthesis for Industrial Applications

3. Artificial Biocatalytic Linear Cascades for Preparation of Organic Molecules

4. Multienzymatic Cascade Reactions via Enzyme Complex by Immobilization

5. New frontiers in enzyme immobilisation: robust biocatalysts for a circular bio-based economy

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