Bacteria encapsulation and rapid antibiotic susceptibility test using a microfluidic microwell device integrating surface-enhanced Raman scattering-Reference-Cited by-同舟云学术

Bacteria encapsulation and rapid antibiotic susceptibility test using a microfluidic microwell device integrating surface-enhanced Raman scattering

Published:2020 Issue:14 Volume:20 Page:2520-2528
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Huang Hsiu-Kang¹²³⁴,Cheng Ho-Wen⁵⁶³⁴,Liao Cheng-Chieh¹²³⁴,Lin Shang-Jyun¹²³⁴,Chen Yi-Zih⁷²³⁴,Wang Juen-Kai⁵⁶³⁴⁸,Wang Yuh-Lin⁵⁶³⁴⁹^ORCID,Huang Nien-Tsu¹²³⁴¹⁰^ORCID

Affiliation:

1. Graduate Institute of Biomedical Electronics and Bioinformatics

2. National Taiwan University

3. Taipei

4. Taiwan

5. Institute of Atomic and Molecular Sciences

6. Academia Sinica

7. Department of Biomechatronics Engineering

8. Center for Condensed Matter Sciences

9. Department of Physics

10. Department of Electrical Engineering

Abstract

We developed a microfluidic microwell device integrating SERS substrate for an efficient bacteria encapsulation and enrichment followed by in situ SERS-AST measurement, which can potentially apply for high throughput and multi-parallel AST.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/D0LC00425A

Reference33 articles.

1. A systematic review of the clinical, public health and cost-effectiveness of rapid diagnostic tests for the detection and identification of bacterial intestinal pathogens in faeces and food

2. Biosensors for Whole-Cell Bacterial Detection

3. Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices