2-Nitroimidazole based fluorescent probes for nitroreductase; monitoring reductive stress in cellulo
Author:
Affiliation:
1. Department of Chemistry
2. Maynooth University
3. National
4. University of Ireland
5. Maynooth
6. Trinity Biomedical Sciences Institute (TBSI)
7. Trinity
8. College Dublin
9. Dublin 2
10. Ireland
Abstract
Two 2-nitroimidazole-1,8-naphthalimide conjugates, 1 and 2, have been synthesised as fluorescence probes for the detection of reductive stress in HeLa cells.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01406F
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5. Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia
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