Multivalent inhibition of the <i>Aspergillus</i> fumigatus KDNase-Reference-Cited by-同舟云学术

Multivalent inhibition of the Aspergillus fumigatus KDNase

Published:2024 Issue:28 Volume:22 Page:5783-5789
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Scalabrini Mathieu¹,Loquet Denis¹,Rochard Camille²,Baudin Marie Mélyne¹,Assailly Coralie¹,Brissonnet Yoan¹,Daligault Franck³^ORCID,Saumonneau Amélie³,Lambert Annie³,Grandjean Cyrille³^ORCID,Deniaud David¹^ORCID,Lottin Paul⁴,Pascual Sagrario⁴^ORCID,Fontaine Laurent⁴^ORCID,Balloy Viviane²,Gouin Sébastien G.¹^ORCID

Affiliation:

1. Nantes Université, CNRS, CEISAM, UMR 6230, F-44000 Nantes, France

2. Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France

3. Nantes Université, CNRS, US2B, UMR 6286, F-44000 Nantes, France 2 rue de la Houssinière, BP 92208, 44322 Nantes Cedex 3, France

4. Institut des Molécules et Matériaux du Mans (IMMM), UMR 6283 CNRS, Le Mans Université, Av. O. Messiaen, 72085 Le Mans cedex 9, France

Abstract

A synthetic polymer of KDN sugar inhibits the AfKDNAse enzyme from the pathogenic fungus Aspergillus fumigatus and decreases its filamentation.

Funder

Centre National de la Recherche Scientifique

Conseil Régional des Pays de la Loire

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00601A

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5. Sialidase Inhibitors with Different Mechanisms