Ultrasound-assisted diastereoselective green synthesis of spiro-fused-γ-lactams functionalized with an amide bond heterocyclic bioisostere <i>via</i> the Ugi azide/domino process coupled strategy-Reference-Cited by-同舟云学术

Ultrasound-assisted diastereoselective green synthesis of spiro-fused-γ-lactams functionalized with an amide bond heterocyclic bioisostere via the Ugi azide/domino process coupled strategy

Published:2024 Issue:26 Volume:22 Page:5289-5295
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Calderón-Rangel David¹,Rentería-Gómez Ángel¹,Cruz-Jiménez Alicia E.¹,Rentería Gómez Manuel A.¹,Jiménez-Halla J. Oscar C.¹^ORCID,Gámez-Montaño Rocío¹^ORCID

Affiliation:

1. Departamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, Col. Noria Alta, Guanajuato C.P. 36050, Gto., Mexico

Abstract

A series of linked-type 1,5-disubstituted tetrazoles (1,5-DS-Ts) were synthesised via IMCR and employed as synthetic platforms to access bound-type polyheterocycles. The sonochemical strategy include a double domino process under green conditions.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00606B

Reference49 articles.

1. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

2. Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide regimens in patients with cancer: a randomised, active-controlled, double-blind, phase 3 trial

3. Cytotoxicity of a Series of Norcantharidin-Inspired Tetrahydroepoxyisoindole Carboxamides

4. Tetrazoles for biomedicine

5. Amide Bond Bioisosteres: Strategies, Synthesis, and Successes