Gas–liquid tubular continuous-flow Pd-catalysed aminocarbonylation process for scalable synthesis of carboxamides-Reference-Cited by-同舟云学术

Gas–liquid tubular continuous-flow Pd-catalysed aminocarbonylation process for scalable synthesis of carboxamides

Published:2024 Issue:15 Volume:14 Page:4245-4255
ISSN:2044-4753
Container-title:Catalysis Science & Technology
language:en
Short-container-title:Catal. Sci. Technol.

Author:

Rodrigues Fábio M. S.¹^ORCID,Masliy Vitaliy¹,Hryhoryev Yaroslav¹,Dias Lucas D.¹²,Carrilho Rui M. B.¹^ORCID,Calvete Mário J. F.¹^ORCID,Takács Attila³,Mikle Gábor³,Kollár László³,Pereira Mariette M.¹^ORCID

Affiliation:

1. Coimbra Chemistry Centre, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal

2. Laboratório de Novos Materiais, Universidade Evangélica de Goiás (UniEvangélica), Anápolis, Brazil

3. Department of General and Inorganic Chemistry and HUN-REN-PTE Selective Chemical Syntheses Research Group, University of Pécs, Ifjúság útja 6, H-7624 Pécs, Hungary

Abstract

We report an efficient continuous flow process, integrating a custom-designed gas input control system coupled with a tubular reactor, for Pd-catalysed aminocarbonylation, which leads to the multigram synthesis of biologically relevant carboxamides.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CY/D4CY00633J

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