Lead-start isothermal polymerase amplification controlled by DNAzymatic switches-Reference-Cited by-同舟云学术

Lead-start isothermal polymerase amplification controlled by DNAzymatic switches

Published:2022 Issue:21 Volume:14 Page:7828-7836
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Yoo Hyebin¹,Lee Ju Young²,Park Ki Soo³^ORCID,Oh Seung Soo¹^ORCID

Affiliation:

1. Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 37673, South Korea

2. Research Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT), Ulsan, 44429, South Korea

3. Department of Biological Engineering, Konkuk University, Seoul, 05029, South Korea

Abstract

Pb2+-controlled molecular switches enabling activation or deactivation of isothermal amplification on demand were developed, preventing nonspecific amplification and allowing quantitative analysis of multiple samples for POC tests even in the field.

Funder

National Research Foundation of Korea

Korea Basic Science Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D1NR07894A

Reference48 articles.

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3. Prevention of pre-PCR mis-priming and primer dimerization improves low-copy-number amplifications

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