A novel magnetic drug delivery nanocomplex with a cisplatin-conjugated Fe3O4 core and a PEG-functionalized mesoporous silica shell for enhancing cancer drug delivery efficiency
Author:
Affiliation:
1. Proteomics & Molecular Cell Physiology Laboratory
2. Department of Zoology
3. School of Life Sciences
4. Bharathiar University
5. Coimbatore-641 046
Abstract
Towards the rapid synthesis and efficient action of a smart drug delivery nanosystem based on coating a layer of PEG functionalized mesoporous silica onto a cisplatin (CDDP) conjugated Fe3O4 nanocomposite.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19274A
Reference14 articles.
1. Responsive Theranostic Systems: Integration of Diagnostic Imaging Agents and Responsive Controlled Release Drug Delivery Carriers
2. Cellular processing of platinum anticancer drugs
3. Nanoscaling Laws of Magnetic Nanoparticles and Their Applicabilities in Biomedical Sciences
4. Bifunctional Binding of Cisplatin to DNA: Why Does Cisplatin Form 1,2-Intrastrand Cross-Links with AG But Not with GA?
5. Controlled PEGylation of Monodisperse Fe3O4 Nanoparticles for Reduced Non-Specific Uptake by Macrophage Cells
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