Synthesis, biological evaluation and mechanism study of a class of cyclic combretastatin A-4 analogues as novel antitumour agents-Reference-Cited by-同舟云学术

Synthesis, biological evaluation and mechanism study of a class of cyclic combretastatin A-4 analogues as novel antitumour agents

Published:2015 Issue:119 Volume:5 Page:98527-98537
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yan Jun¹²³⁴,Pang Yanqing¹²³⁴,Chen Jie¹²³⁴,Sheng Jianfei¹²³⁴,Hu Jinhui¹²³⁴,Huang Ling¹²³⁴,Li Xingshu¹²³⁴

Affiliation:

1. School of Pharmaceutical Sciences

2. Sun Yat-sen University

3. Guangzhou

4. China

Abstract

In the search for novel antitumor agents, a series of cyclic CA-4 analogues bearing amide group, A–B or B–C ring condensation, and CC or CN bond in the B ring were designed, synthesized and identified as microtubule inhibitors.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19270F

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