Organometallic Ru(ii), Rh(iii) and Re(i) complexes of sterane-based bidentate ligands: synthesis, solution speciation, interaction with biomolecules and anticancer activity

Author:

Pivarcsik Tamás12ORCID,Kiss Márton A.2ORCID,Rapuš Uroš3ORCID,Kljun Jakob3ORCID,Spengler Gabriella14ORCID,Frank Éva2ORCID,Turel Iztok3ORCID,Enyedy Éva A.12ORCID

Affiliation:

1. MTA-SZTE Lendület Functional Metal Complexes Research Group, Department of Molecular and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7-8., H–6720 Szeged, Hungary

2. Department of Molecular and Analytical Chemistry, University of Szeged, Dóm tér 7-8., H–6720 Szeged, Hungary

3. Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, SI–1000 Ljubljana, Slovenia

4. Department of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary

Abstract

Synthesis, characterization, solution speciation, binding affinity towards biomolecules and anticancer activity of organometallic Ru(ii), Rh(iii) and Re(i) complexes of (N,N) donor 5α-dihydrotestosterone-based hybrid ligands.

Funder

Innovációs és Technológiai Minisztérium

Univerza v Ljubljani

Javna Agencija za Raziskovalno Dejavnost RS

Magyar Tudományos Akadémia

European Cooperation in Science and Technology

National Research, Development and Innovation Office

Publisher

Royal Society of Chemistry (RSC)

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