Ethionamide biomimetic activation and an unprecedented mechanism for its conversion into active and non-active metabolites
Author:
Affiliation:
1. CNRS
2. LCC (Laboratoire de Chimie de Coordination)
3. F-31077 Toulouse, Cedex 4
4. France
5. Université de Toulouse
Abstract
We propose that sulfinic acid is neither a precursor of the iminoyl radical nor an intermediate of the ethionamide active metabolite.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01561A
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