Theoretical study of vesicle shapes driven by coupling curved proteins and active cytoskeletal forces
Author:
Affiliation:
1. Faculty of Health Sciences
2. University of Ljubljana
3. Ljubljana
4. Slovenia
5. Faculty of Electrical Engineering
6. Department of Chemical and Biological Physics
7. Weizmann Institute of Science
8. Rehovot 7610001
9. Israel
Abstract
Simulations show that active protrusive forces induced by curved membrane proteins enhance their aggregation and drive a transition to flat pancake-shaped vesicles. This transition resembles the sheet-like protrusions (lamellipodia) of cells.
Funder
Javna Agencija za Raziskovalno Dejavnost RS
Israel Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/SM/C8SM02356E
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