An efficient route to N-alkylated 3,4-dihydroisoquinolinones with substituents at the 3-position-Reference-Cited by-同舟云学术

An efficient route to N-alkylated 3,4-dihydroisoquinolinones with substituents at the 3-position

Published:2018 Issue:11 Volume:8 Page:6146-6151
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tazawa Aoi¹²³⁴⁵,Ando Junki¹²³⁴,Ishizawa Kohei¹²³⁴,Azumaya Isao⁵⁶⁷⁴^ORCID,Hikawa Hidemasa⁵⁶⁷⁴^ORCID,Tanaka Minoru¹²³⁴

Affiliation:

1. Sohyaku Innovative Research Division

2. Mitsubishi Tanabe Pharma Corporation

3. Yokohama-shi

4. Japan

5. Faculty of Pharmaceutical Sciences

6. Toho University

7. Funabashi

Abstract

N-Alkylated 3,4-dihydroisoquinolinone derivatives could be synthesized by N-alkylation of 3,3′-dimethyl-3,4-dihydroisoquinoline derivatives followed by oxidation of the resulting iminium salts.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C7RA13627G

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