A new bis-pyrazolylpyridine ruthenium(iii) complex as a potential anticancer drug: in vitro and in vivo activity in murine colon cancer

Author:

Lazić Dejan12345,Scheurer Andreas678910ORCID,Ćoćić Dušan111245ORCID,Milovanović Jelena13211145,Arsenijević Aleksandar13211145,Stojanović Bojana13211145,Arsenijević Nebojša13211145,Milovanović Marija13211145,Rilak Simović Ana11151645ORCID

Affiliation:

1. Department of Surgery

2. Faculty of Medical Sciences

3. University of Kraujevac

4. 34000 Kragujevac

5. Serbia

6. Inorganic Chemistry

7. Department of Chemistry and Pharmacy

8. University of Erlangen-Nürnberg

9. Erlangen

10. Germany

11. University of Kragujevac

12. Faculty of Science

13. Center for Molecular Medicine and Stem Cell Research

14. Kragujevac

15. Institute for Information Technologies Kragujevac

16. Department of Natural Sciences

Abstract

Ru pincer-type complex 1 reduced primary tumor growth and the number and growth of lung and liver metastases, significantly prolonging the survival rate of treated mice.

Funder

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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