Muscle-on-a-chip with an on-site multiplexed biosensing system for in situ monitoring of secreted IL-6 and TNF-α-Reference-Cited by-同舟云学术

Muscle-on-a-chip with an on-site multiplexed biosensing system for in situ monitoring of secreted IL-6 and TNF-α

Published:2019 Issue:15 Volume:19 Page:2568-2580
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Ortega María A.¹²³⁴,Fernández-Garibay Xiomara¹²³⁴,Castaño Albert G.¹²³⁴,De Chiara Francesco¹²³⁴,Hernández-Albors Alejandro¹²³⁴,Balaguer-Trias Jordina¹²³⁴,Ramón-Azcón Javier¹²³⁴^ORCID

Affiliation:

1. Institute for Bioengineering of Catalonia (IBEC)

2. The Barcelona Institute of Science and Technology (BIST)

3. Barcelona

4. Spain

Abstract

We present an integrated microdevice capable of simultaneous, in situ cell stimulation and analyte detection. As a proof of concept, the detection of secreted cytokines from an engineered 3D skeletal muscle tissue was measured.

Funder

H2020 European Research Council

Ministerio de Economía, Industria y Competitividad, Gobierno de España

Generalitat de Catalunya

“la Caixa” Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/LC/C9LC00285E

Reference25 articles.