Effect of the abolition of intersubunit salt bridges on allosteric protein structural dynamics-Reference-Cited by-同舟云学术

Effect of the abolition of intersubunit salt bridges on allosteric protein structural dynamics

Published:2021 Issue:23 Volume:12 Page:8207-8217
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Choi Minseo¹²³⁴⁵^ORCID,Kim Jong Goo⁶⁷³⁴,Muniyappan Srinivasan⁶⁷³⁴,Kim Hanui¹²³⁴⁵,Kim Tae Wu⁶⁷³⁴^ORCID,Lee Yunbeom¹²³⁴⁵,Lee Sang Jin¹²³⁴⁵^ORCID,Kim Seong Ok⁶⁷³⁴,Ihee Hyotcherl¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Korea Advanced Institute of Science and Technology (KAIST)

3. Daejeon 34141

4. Republic of Korea

5. KI for the BioCentury

6. Center for Nanomaterials and Chemical Reactions

7. Institute for Basic Science (IBS)

Abstract

The structural and functional roles of salt bridges in the allosteric structural transition of homodimeric hemoglobin are investigated by time-resolved X-ray solution scattering.

Funder

Institute for Basic Science

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC01207J

Reference55 articles.

1. Allosteric Communication in the Tryptophan Synthase Bienzyme Complex: Roles of the β-Subunit Aspartate 305−Arginine 141 Salt Bridge

2. Structural and functional characterization of D109H and R69C mutant versions of human αB-crystallin: The biochemical pathomechanism underlying cataract and myopathy development