Synthesis of fluorinated spiro-1,3-oxazines and thiazines via Selectfluor-mediated intramolecular cyclization

Author:

Gogoi Chinu12,Saikia Ujwal Pratim3,Borah Priyam1,Saikia Trishna12,Bora Anamika12,Rastogi Gaurav K.1,Pahari Pallab12ORCID

Affiliation:

1. Chemical Science and Technology Division, CSIR-North East Institute of Science and Technology, Jorhat-785006, Assam, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

3. Department of Chemistry, Sadiya College, Tinsukia-786157, Assam, India

Abstract

An intramolecular fluoronative spirocyclization for the synthesis of fluorine-substituted spiro-1,3-oxazine and spiro-1,3-thiazine derivatives is described.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Reference51 articles.

1. A synthon approach to spiro compounds

2. Nomenclature, Synthesis and Applications of Spirocyclic Compounds , ed. D. Habibi and M. Beiranvand , Cambridge Scholars Publishing , Lady Stephenson Library, Newcastle upon Tyne, NE6 2PA, UK , 2023

3. Spirocyclic derivatives as antioxidants: a review

4. Spirocyclic Compounds in Fragrance Chemistry: Synthesis and Olfactory Properties

5. Spirocyclic Motifs in Natural Products

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